Objectives: To examine the association between psychiatric and non-psychiatric comorbidity and 28-day mortality among patients with psychiatric disorders and COVID-19. Methods: Multicenter observational retrospective cohort study of adult patients with psychiatric disorders hospitalized with laboratory-confirmed COVID-19 at 36 Greater Paris university hospitals (January 2020-May 2021) (n=3,768). First, we searched for different subgroups of patients according to their psychiatric and non-psychiatric comorbidities through cluster analysis. Next, we compared 28-day all-cause mortality rates across the identified clusters, while taking into account sex, age, and the number of medical conditions. Results: We found five clusters of patients with distinct psychiatric and non-psychiatric comorbidity patterns. Twenty-eight-day mortality in the cluster of patients with mood disorders was significantly lower than in other clusters. There were no significant differences in mortality across other clusters. Conclusion: All psychiatric and non-psychiatric conditions may be associated with increased mortality in patients with psychiatric disorders and COVID-19. The lower risk of death among patients with mood disorders might be in line with the potential beneficial effect of certain antidepressants in COVID-19, but requires further research. These findings may help identify at-risk patients with psychiatric disorders who should benefit from vaccine booster prioritization and other prevention measures.

Fragile X Syndrome (FXS) and Down Syndrome (DS) read better than expected for their mental age. We have measured three basic reading skills (word recognition, phonological awareness, and reading comprehension), and two standard intellectual and verbal measures: the McCarthy Scales of Children's Abilities and Peabody Picture Vocabulary Tests. The tests were applied to 16 adolescents classified as FXS (M = 14.74 years old, SD = 4.03) and 16 adolescents classified as DS (M = 15.59 years old, SD = 2.35). For comparison purposes, the reading tests were also applied to a typical develop group of 70 children aged between 4.8 and 7.0 years (M = 6.11, SD = 0.71). Children with DS and FXS exhibited verbal skills superior to their cognitive development, especially in the FXS group. In reading performance, FXS showed a reading level corresponding to 5/6 their age, and for SD 6/7 of the equivalent reading age, however, both groups exhibited a similar reading performance in the three reading skills measured, when nonverbal mental age was controlled.

Las personas con síndrome de X frágil (FXS) y con síndrome de Down (DS) leen mejor de lo esperado para su edad mental. Hemos medido tres habilidades básicas de lectura (reconocimiento de palabras, conciencia fonológica y comprensión de lectura), y dos medidas estándar intelectual y verbal: Escalas McCarthy de capacidades de los niños y los Peabody Picture Vocabulary Tests. Las pruebas se aplicaron a 16 adolescentes clasificados como FXS (M = 14.74 años, DT = 4.03) y 16 adolescentes clasificados como DS (M = 15.59 años, SD = 2.35). Para fines de comparación, las pruebas de lectura también se aplicaron a un grupo de desarrollo normal de 70 niños de entre 4.8 y 7 años (M = 6.11, DT = 0.71). Los niños con DS y FXS mostraron habilidades verbales superiores a su desarrollo cognitivo, especialmente en el grupo FXS. En el rendimiento de lectura, FXS mostraron un nivel de lectura correspondiente a 5/6 de su edad, y para SD 6/7 de la edad de lectura equivalente; sin embargo, ambos grupos mostraron un rendimiento de lectura similar en las tres habilidades de lectura medidas, cuando la edad mental no verbal fue controlada.

Se analizan los componentes básicos para la adquisición de la lectura en castellano mediante la aplicación del modelo logístico lineal de Fisher (Linear Logistic Test Model [LLTM]). Participaron en el estudio 245 niños y niñas de edades comprendidas entre los 4 y los 9 años a los que se administró una extensa batería diseñada para evaluar distintos procesos básicos para la lectura (PROBALES). Se aplicaron técnicas de análisis factorial para seleccionar un subconjunto de ítems que mostrasen ajuste al modelo de Rasch. El LLTM permitió confirmar la validez del modelo teórico según el cual el aprendizaje de la lectura descansa en el desarrollo de tres habilidades básicas: reconocimiento de palabras, conciencia fonológica y comprensión de la lectura. Se muestra la capacidad predictiva del modelo mediante análisis discriminante, y se constata que se clasificó correctamente en su curso escolar al 68% de los participantes.

The basic components for the acquisition of reading in Spanish are analyzed by using the Fisher Linear Logistic Test Model (LLTM). An extensive battery designed to assess different Basic Processes for Reading (PROBALES, acronym in Spanish) was applied to 245 children aged 4 to 9. Factor analysis techniques were used to select a subset of items that would adjust to the Rasch model. The LLTM confirmed the validity of the theoretical model which states that reading acquisition relies on the development of three basic skills: word recognition, phonological awareness, and reading comprehension. The theoretical model's predictive ability is shown by discriminant analysis, thereby confirming that 68% of participants were correctly classified in their school grade.

Las investigaciones realizadas en el último medio siglo revelan que la gran mayoría de los sordos escolarizados no alcanzan el nivel mínimo o funcional para poder comunicarse por escrito. En este artículo revisamos las investigaciones que en las últimas décadas han intentado establecer las causas y las posibles soluciones para la mejora de la lectura en sujetos sordos. De modo particular analizamos los componentes lingüísticos y los códigos signados, fonológicos, y dactílicos. En la última parte del artículo proponemos un modelo de lectura para sordos que es similar al utilizado en los sujetos oyentes que son disléxicos fonológicos, incluyendo de forma destacada las siguientes estrategias: dactilología, lectura labial, implantes cocleares, cued-speech, lengua de signos y estímulos kinestésicos, con el propósito de mejorar el componente fonológico.

Research carried out during the last 50 years has shown that the majority of schooled deafpeopledo not reach the minimal or functional level for written communication. In this article,a review of the investigation attempting to establish the causes and possiblesolutions for improving reading in deaf children is presented. In particular, we analyze the linguistic components and the signed, phonological and dactylic codes. Finally, we propose a reading model for deaf people; this model is similar to the model proposed for individuals with phonological dyslexia. The following strategies for improving their phonological components are emphasized: dactylology, lip reading, cochlear implants, cued-speech, sign language and kinesthetic stimulation.